![]() Thymol is suggested to potentiate GABA A receptors through an allosteric binding site. ThymeĮxtract significantly reduces production and gene expression of proinflammatory mediators, TNF-α, IL-1B, and IL-6, and carvacrol is reported to activate PPARα and PPARγ and suppresses COX-2 expression, and inhibits AChE Aqueous extract showed high antiviral activity against HSV-1, HSV-2 and an acyclovir-resistant strain of HSV-1. Both thymol and carvacrol have also been suggested being responsible for the antioxidant activity while others attributed the antioxidative action to labiate acid and rosmarinic acid. Thymus vulgarisĪnd its volatile extracts possess high antioxidant activity and rosmarinic acid is identified as the predominant phenolic compound. It contains thymol, carvacrol, p-cymene, α-pinene, terpineol, v-terpinene, geraniol, linalool and traces of cineole. Most important constituent of the plant is the EO which is used for many purposes. Aerial parts contain volatile oil, flavonoids, sterols/triterpenes, tannins, anthraquinones, and cyanogenic glycosides. Oil is used as a disinfectant and antiseptic, probably due to its phenolic content and for scenting soaps, making perfumes, and as a flavoring agent for food. It is also an anesthetic, and irritant to skin and mucous membranes. As a nervine tonic, it is used in the treatment of epilepsy, and also used in dyspnea and asthma, diarrhea, dyspepsia with flatulence, gonorrhea, leucorrhea, and visceral catarrh. ![]() In Unani medicine, aerial parts are regarded analgesic, anti-inflammatory, expectorant, digestive, carminative, emmenagogue, anthelmintic, lithotriptic, diuretic, aphrodisiac, and to improve digestion and appetite. It was also used as incense by the Greeks and placed in coffins to assure passage into the next life. It was used for embalming by Egyptians, used in baths by Greeks, and Romans purified their rooms with it. Is a bushy, evergreen subshrub, that was known to ancient Egyptians, Greeks and Romans.
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